MOTS-c
Mitochondrial Research Peptide
Size: 10mg



MOTS-c is a mitochondrial-derived peptide studied for AMPK activation, insulin sensitivity, and metabolic regulation in cellular research.
MOTS-c (Mitochondrial-Derived Peptide)
16-amino-acid peptide encoded within the mitochondrial 12S rRNA
Studied in cellular metabolism and energy-homeostasis research
Investigated for roles in metabolic-stress and insulin-sensitivity models
Often referenced in exercise-mimetic research
Acts as a signaling peptide between mitochondria and the nucleus
Research Use Notes
Supplied as lyophilized powder
Requires reconstitution before use
Research Water required for mixing (sold separately)
Swirl gently, never shake
Storage
Store lyophilized vial frozen for long-term holding
Keep reconstituted solution at 2 to 8°C
Stable refrigerated for up to 28 days
Handling
Maintain sterile workflow during reconstitution
For laboratory research use only
Certificate of Analysis
Independently 8x Tested by Kovera Labs and/or ILS Labs
(Click here to learn about 8x testing)
All certificates are issued by independent ISO-accredited laboratories. Lot-specific documents are made available to qualified research professionals on request.
Frequently Bought Together
Commonly paired to support consistent, reliable experimentation.
Compound Information
Technical specifications
What Is MOTS-c?
Mitochondrial ORF of the 12S rRNA type-c
- Type
- Mitochondrial-derived peptide
- CAS Number
- 1627580-64-6
- Molecular Weight
- 2,174.6 g/mol
- Amino Acids
- 16
Stability Information
-20°C
24+ months
2-8°C
~30 days
Sources & References
Peer-reviewed research
MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
2015 · DOI: 10.1016/j.cmet.2015.02.009 · Lee C, Cohen P, et al.
View SourceNature CommunicationsMOTS-c Is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline
2021 · DOI: 10.1038/s41467-020-20790-0 · Reynolds JC, et al.
View SourcePubMed CentralMOTS-c in Metabolic Regulation and Mitochondrial Function — Review
Review
View SourcePubChemMOTS-c Compound Information
View SourceClinicalTrials.govMOTS-c Clinical Research Registry
View SourceProducts are intended solely for laboratory and scientific research purposes. Not intended for human consumption, veterinary use, diagnosis, treatment, cure, or prevention of disease.


All the research compounds you need, with the confidence that every batch is 8× tested before it ships.
Subscribe to our Newsletter
Subscribe to our newsletter to get daily insights, news, updates.
















